This week in Science
Anyone else tired of Noah's Ark? Great, then I have some really interesting articles in the latest Science we can read instead. First, the Xenopus tropicalis genome has been published. Results are pretty much as expected: 20,000 predicted genes in a 1.7 Gb genome (ten chromosomes). A third is transposable element, and it shares a great deal of conserved synteny with the chromosomes of other vertebrates (notably chicken and human). Hellsten et al. 2010. The Genome of the Western Clawed Frog Xenopus tropicalis . Science 328:633-636. Also interesting in the genome-sequencing department is the report of the complete genomes of a human family of four (two parents, two children). The research team directly estimated the mutation rate as 1.1 x 10 -8 . That should be a useful piece of knowledge. Roach et al. 2010. Analysis of Genetic Inheritance in a Family Quartet by Whole-Genome Sequencing . Science 328:636-639. Edwards et al. have an interesting review on the origin of C4 gr